Ultra-wideband temperature dependent dielectric spectroscopy of porcine tissue and blood in the microwave frequency range
The knowledge of frequency and temperature dependent dielectric properties of tissue is essential to develop ultra-wideband diagnostic technologies, such as a non-invasive temperature monitoring system during hyperthermia treatment. To this end, we characterized the dielectric properties of animal liver, muscle, fat and blood in the microwave frequency range … celý popis
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10. 04. 2019
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| Abstract | The knowledge of frequency and temperature dependent dielectric properties of tissue is essential to develop ultra-wideband diagnostic technologies, such as a non-invasive temperature monitoring system during hyperthermia treatment. To this end, we characterized the dielectric properties of animal liver, muscle, fat and blood in the microwave frequency range from 0.5 GHz to 7 GHz and in the temperature range between 30 °C and 50 °C. The measured data were modeled to a two-pole Cole-Cole model and a second-order polynomial was introduced to fit the Cole-Cole parameters as a function of temperature. The parametric model provides access to the dielectric properties of tissue at any frequency and temperature in the specified range. |
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| AbstractList | The knowledge of frequency and temperature dependent dielectric properties of tissue is essential to develop ultra-wideband diagnostic technologies, such as a non-invasive temperature monitoring system during hyperthermia treatment. To this end, we characterized the dielectric properties of animal liver, muscle, fat and blood in the microwave frequency range from 0.5 GHz to 7 GHz and in the temperature range between 30 °C and 50 °C. The measured data were modeled to a two-pole Cole-Cole model and a second-order polynomial was introduced to fit the Cole-Cole parameters as a function of temperature. The parametric model provides access to the dielectric properties of tissue at any frequency and temperature in the specified range. |
| ArticleNumber | 1707 |
| Author | Sachs, Jürgen Schilling, Susanne Fiser, Ondrej Helbig, Marko Ley, Sebastian Vrba, Jan |
| AuthorAffiliation | 1 Biosignal Processing Group, Technische Universität Ilmenau, 98693 Ilmenau, Germany; susanne.schilling@tu-ilmenau.de (S.S.); marko.helbig@tu-ilmenau.de (M.H.) 2 Department of Biomedical Technology, Faculty of Biomedical Engineering, CTU in Prague, 272 01 Kladno, Czech Republic; ondrej.fiser@fbmi.cvut.cz 3 Department of Electromagnetic Field, Faculty of Electrical Engineering, CTU in Prague, 160 00 Prague, Czech Republic; vrba@fel.cvut.cz 5 ILMSENS GmbH, 98693 Ilmenau, Germany 4 Electronic Measurements and Signal Processing Group, Technische Universität Ilmenau, 98693 Ilmenau, Germany; juergen.sachs@tu-ilmenau.de |
| AuthorAffiliation_xml | – name: 3 Department of Electromagnetic Field, Faculty of Electrical Engineering, CTU in Prague, 160 00 Prague, Czech Republic; vrba@fel.cvut.cz – name: 4 Electronic Measurements and Signal Processing Group, Technische Universität Ilmenau, 98693 Ilmenau, Germany; juergen.sachs@tu-ilmenau.de – name: 2 Department of Biomedical Technology, Faculty of Biomedical Engineering, CTU in Prague, 272 01 Kladno, Czech Republic; ondrej.fiser@fbmi.cvut.cz – name: 5 ILMSENS GmbH, 98693 Ilmenau, Germany – name: 1 Biosignal Processing Group, Technische Universität Ilmenau, 98693 Ilmenau, Germany; susanne.schilling@tu-ilmenau.de (S.S.); marko.helbig@tu-ilmenau.de (M.H.) |
| Author_xml | – sequence: 1 givenname: Sebastian orcidid: 0000-0002-5202-3082 surname: Ley fullname: Ley, Sebastian email: sebastian.ley@tu-ilmenau.de organization: Biosignal Processing Group, Technische Universität Ilmenau, 98693 Ilmenau, Germany. sebastian.ley@tu-ilmenau.de – sequence: 2 givenname: Susanne surname: Schilling fullname: Schilling, Susanne email: susanne.schilling@tu-ilmenau.de organization: Biosignal Processing Group, Technische Universität Ilmenau, 98693 Ilmenau, Germany. susanne.schilling@tu-ilmenau.de – sequence: 3 givenname: Ondrej surname: Fiser fullname: Fiser, Ondrej email: ondrej.fiser@fbmi.cvut.cz organization: Department of Biomedical Technology, Faculty of Biomedical Engineering, CTU in Prague, 272 01 Kladno, Czech Republic. ondrej.fiser@fbmi.cvut.cz – sequence: 4 givenname: Jan surname: Vrba fullname: Vrba, Jan email: vrba@fel.cvut.cz organization: Department of Electromagnetic Field, Faculty of Electrical Engineering, CTU in Prague, 160 00 Prague, Czech Republic. vrba@fel.cvut.cz – sequence: 5 givenname: Jürgen surname: Sachs fullname: Sachs, Jürgen email: juergen.sachs@tu-ilmenau.de, juergen.sachs@tu-ilmenau.de organization: ILMSENS GmbH, 98693 Ilmenau, Germany. juergen.sachs@tu-ilmenau.de – sequence: 6 givenname: Marko orcidid: 0000-0001-6167-9748 surname: Helbig fullname: Helbig, Marko email: marko.helbig@tu-ilmenau.de organization: Biosignal Processing Group, Technische Universität Ilmenau, 98693 Ilmenau, Germany. marko.helbig@tu-ilmenau.de |
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| Keywords | ultra-wideband open-ended coaxial probe dielectric spectroscopy temperature dependent dielectric properties of blood, fat, liver, muscle M-sequence |
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| SubjectTerms | Algorithms Animals Blood - radiation effects Dielectric Spectroscopy Electric Impedance Fat Fats - radiation effects Humans Liver Liver - physiology Liver - radiation effects M-sequence Microwaves Models, Biological Muscle Muscles - physiology Muscles - radiation effects Open-ended coaxial probe Swine Temperature Temperature dependent dielectric properties of blood temperature dependent dielectric properties of blood, fat, liver, muscle Ultra-wideband |
| Title | Ultra-wideband temperature dependent dielectric spectroscopy of porcine tissue and blood in the microwave frequency range |
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