In vitro evaluation of the composition and acaricidal efficacy of Urtica fissa leaf ethyl acetate extract against Sarcoptes scabiei mites

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In veterinary medicine, natural products provide an alternative to chemical agents for mite management. In the present study, the acaricidal efficacy of Urtica fissa leaf ethyl acetate extract against Sarcoptes scabiei mites was examined. The chemical composition of the extract was determined using liquid chromatography-mass spectrometry (LC-MS) analysis. The ethyl acetate extract was found to be extremely toxic to mites at a concentration of 100 mg/ml (m/v), killing all S. scabiei within two hours. The median lethal time (LT50) values for ethyl acetate extract concentrations of 25, 50, and 100 mg/ml against S. scabiei were 1.706, 1.204, and 0.750 h, respectively. The median lethal dosage (LC50) for S. scabiei was 19.14 mg/ml at two hours. The chemical composition of the ethyl acetate extract was evaluated using LC-MS, showing that the major components were schaftoside (8.259%), carnosol (6.736%), prostaglandin A2 (5.94%), 13(S)-HpOTrE (4.624%), nandrolone (4.264%), 1H-indole3-carboxaldehyde (4.138%), 9-oxoODE (3.206%), and stearidonic acid (2.891%). In conclusion, these findings indicate that Urtica fissa contains promising new acaricidal compounds capable of successfully controlling animal mites. … celý popis

Podrobná bibliografie

Hlavní autor

Fei Liao

Další autoři

Taotao Bao, Guangyao Tao, Yanchun Hu, Changquan Han

Typ dokumentu

Články

Fyzický popis

Ilustrace

Publikováno v

Veterinární medicína. -- ISSN 0375-8427. -- Roč. 68, č. 5 (2023), s. 200-207

Témata

méně…

ANIMAL DISEASES

PARASITOSES

SKIN DISEASES

sarcoptic mange

SARCOPTES SCABIEI

THERAPY

DRUG PLANTS

URTICA

LEAVES

EXTRACTS

CHEMICAL COMPOSITION

CHROMATOGRAPHY

MASS SPECTROMETRY

DOSAGE

EFFICIENCY

IN VITRO EXPERIMENTATION

choroby zvířat

infekční choroby

parazitózy

kožní nemoci

svrab

sarkoptóza

Sarcoptes scabiei

terapie

léčivé rostliny

kopřiva

listy

extrakty

chemické složení

chromatografie

hmotnostní spektrometrie

dávkování

účinnost

akaricidní vlastnosti

pokusy in vitro

Urtica fissa

více… méně…

Popis jednotky

2 barevné fotografie, 1 graf, 4 tabulky

Bibliografie

Literatura na s. 206-207