Výsledky vyhledávání - "microsatellite stable"
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1Hlavní autor Ree, Anne Hansen, Šaltytė Benth, Jūratė, Hamre, Hanne M., Kersten, Christian, Hofsli, Eva, Guren, Marianne G., Sorbye, Halfdan, Johansen, Christin, Negård, Anne, Bjørnetrø, Tonje, Nilsen, Hilde L., Berg, Jens P., Flatmark, Kjersti, Meltzer, Sebastian“…Background We evaluated first-line treatment of metastatic microsatellite-stable colorectal cancer with short-course oxaliplatin-based chemotherapy alternating with immune checkpoint blockade…”
Publikováno v British journal of cancer (29. 06. 2024)
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2Hlavní autor Xiao, Yunyun, Yu, XiaoChuan, Wang, Yaping, Song, Guangyao, Liu, Ming, Wang, Daqing, Wang, Huali“…) and microsatellite stable (MSS) endometrial carcinoma (EC), and provide potential immunotherapy directions for MSS patients…”
Publikováno v Scientific reports (14. 02. 2024)
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3Hlavní autor Bessudo, Alberto, Haseeb, Abdul Mustajeeb, Reeves, James A., Zhu, Xiaofu, Wong, Lucas, Giranda, Vincent, Suttner, Leah, Liu, Fang, Chatterjee, Manash, Sharma, Sunil“…Pembrolizumab, a monoclonal antibody against PD-1, has shown limited efficacy in patients with microsatellite stable or mismatch repair proficient (MSS/pMMR…”
Publikováno v Clinical colorectal cancer (01. 09. 2024)
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4Hlavní autor Lemech, Charlotte, Dredge, Keith, Bampton, Darryn, Hammond, Edward, Clouston, Andrew, Waterhouse, Nigel J, Stanley, Amanda C, Leveque-El Mouttie, Lucie, Chojnowski, Grace M, Haydon, Andrew, Pavlakis, Nick, Burge, Matthew, Brown, Michael P, Goldstein, David“… dose escalation with microsatellite stable metastatic colorectal cancer (MSS mCRC) and metastatic pancreatic ductal adenocarcinoma (mPDAC) expansion cohorts…”
Publikováno v Journal for immunotherapy of cancer (01. 01. 2023)
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5Hlavní autor Jamal, Sumayah, Selvaggi, Giovanni“… cancer.MethodsStudy ENB-003-101 (MK-3475-951) is a multicenter, Phase 1/2, open-label study of ENB-003 in combination with pembrolizumab in adult subjects with advanced refractory solid tumors. The Part…”
Publikováno v Journal for immunotherapy of cancer (01. 11. 2023)
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6Hlavní autor Lemech, Charlotte, Dredge, Keith, Bampton, Darryn, Hammond, Edward, Clouson, Andrew, Waterhouse, Nigel, Stanley, Amanda, Leveque-ElMouttie, Lucie, Chojnowski, Grace, Haydon, Andrew, Pavlakis, Nick, Burge, Matthew, Brown, Michael, Goldstein, David“…BackgroundPixatimod is a novel immunomodulatory agent which stimulates dendritic cells (DC) via Toll-Like Receptor 9 (TLR9) pathway to activate natural killer…”
Publikováno v Journal for immunotherapy of cancer (01. 11. 2021)
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7Hlavní autor OGINO, Shuji, MEYERHARDT, Jeffrey A, KAWASAKI, Takako, CLARK, Jeffrey W, RYAN, David P, KULKE, Matthew H, ENZINGER, Peter C, WOLPIN, Brian M, LODA, Massimo, FUCHS, Charles S“…) in 30 metastatic microsatellite stable colorectal carcinomas in phase I/II clinical trials of combination chemotherapy…”
Publikováno v Virchows Archiv : an international journal of pathology (01. 05. 2007)
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8Hlavní autor Saunders, M P, Graham, J, Cunningham, D, Plummer, R, Cook, S, Church, D, Kerr, R, Thangue, N La, Kerr, D J“…Abstract Background CXD101 is a histone–deacetylase inhibitor which reactivates the patient’s immune system by increasing tumour expression of MHC I & II,…”
Publikováno v Annals of oncology (01. 10. 2019)
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9Hlavní autor Saunders, M.P., Graham, J., Cunningham, D., Plummer, R., Cook, S., Church, D., Kerr, R., Thangue, N La, Kerr, D.J.“…CXD101 is a histone–deacetylase inhibitor which reactivates the patient’s immune system by increasing tumour expression of MHC I & II, tumoural infiltration by…”
Publikováno v Annals of oncology (01. 10. 2019)
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10Hlavní autor Gylling, A, Abdel-Rahman, W M, Juhola, M, Nuorva, K, Hautala, E, Järvinen, H J, Mecklin, J-P, Aarnio, M, Peltomäki, P“…: To determine whether or not gastric cancer is a true HNPCC spectrum malignancy. Subjects and methods…”
Publikováno v Gut (01. 07. 2007)
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11Hlavní autor Wynter, C V A, Walsh, M D, Higuchi, T, Leggett, B A, Young, J, Jass, J R“…) in subjects with hyperplastic polyposis (group II). DNA methylation was tested in methylated in tumour (MINT) loci (1, 2, 12, 31…”
Publikováno v Gut (01. 04. 2004)
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12Hlavní autor Lee, Saet-byul, Cha, Junhoe, Kim, Im-kyung, Yoon, Joo Chun, Lee, Hyo Joon, Park, Sang Woo, Cho, Sunjung, Youn, Dong-Ye, Lee, Heyja, Lee, Choong Hwan, Lee, Jae Myun, Lee, Kang Young, Kim, Jongsun“…•We demonstrated a simple assay of NK cell activity from whole blood.•The measurement of secreted IFN-γ from NK cell enables high-throughput screening.•The NKA…”
Publikováno v Biochemical and biophysical research communications (14. 03. 2014)
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14Hlavní autor Baltgalvis, Kristen A., Lamb, Kelsey N., Symons, Kent T., Wu, Chu-Chiao, Hoffman, Melissa A., Snead, Aaron N., Song, Xiaodan, Glaza, Thomas, Kikuchi, Shota, Green, Jason C., Rogness, Donald C., Lam, Betty, Rodriguez-Aguirre, Maria E., Woody, David R., Eissler, Christie L., Rodiles, Socorro, Negron, Seth M., Bernard, Steffen M., Tran, Eileen, Pollock, Jonathan, Tabatabaei, Ali, Contreras, Victor, Williams, Heather N., Pastuszka, Martha K., Sigler, John J., Pettazzoni, Piergiorgio, Rudolph, Markus G., Classen, Moritz, Brugger, Doris, Claiborne, Christopher, Plancher, Jean-Marc, Cuartas, Isabel, Seoane, Joan, Burgess, Laurence E., Abraham, Robert T., Weinstein, David S., Simon, Gabriel M., Patricelli, Matthew P., Kinsella, Todd M.“… This compound selectively engages a cysteine (C727) located in a region of the helicase domain subject to interdomain movement during DNA unwinding…”
Publikováno v Nature (London) (09. 05. 2024)
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15Hlavní autor Phipps, Amanda I, Limburg, Paul J, Baron, John A, Burnett-Hartman, Andrea N, Weisenberger, Daniel J, Laird, Peter W, Sinicrope, Frank A, Rosty, Christophe, Buchanan, Daniel D, Potter, John D, Newcomb, Polly A“… (microsatellite stable [MSS] or MSI…”
Publikováno v Gastroenterology (New York, N.Y. 1943) (01. 01. 2015)
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16Hlavní autor Tommasi, Orazio De, Marchetti, Matteo, Tripepi, Marta, Bigardi, Sofia, Incognito, Giosuè Giordano, Tuninetti, Valentina, Facchetti, Emma, Tasca, Giulia, Noventa, Marco, Saccardi, Carlo, Tozzi, Roberto, Spagnol, Giulia“…Cancer immunotherapy through the use of PD-1/PD-L1 inhibitors have shown significant promise in endometrial carcinoma (EC), particularly in tumors with…”
Publikováno v Journal of clinical medicine (10. 01. 2025)
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17Hlavní autor Yan, Helen H N, Siu, Hoi Cheong, Ho, Siu Lun, Yue, Sarah S K, Gao, Yang, Tsui, Wai Yin, Chan, Dessy, Chan, April S, Wong, Jason W H, Man, Alice H Y, Lee, Bernard C H, Chan, Annie S Y, Chan, Anthony K W, Hui, Ho Sang, Cheung, Arthur K L, Law, Wai Lun, Lo, Oswens S H, Yuen, Siu Tsan, Clevers, Hans, Leung, Suet Yi“… in EOCRCs.DesignWe established paired cancer (n=32) and normal organoids (n=18) from 20 patients enriched in microsatellite-stable EOCRC…”
Publikováno v Gut (01. 12. 2020)
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19Hlavní autor Svrcek, Magali, El-Murr, Nizar, Wanherdrick, Kristell, Dumont, Sylvie, Beaugerie, Laurent, Cosnes, Jacques, Colombel, Jean-Frédéric, Tiret, Emmanuel, Fléjou, Jean-François, Lesuffleur, Thécla, Duval, Alex“… We studied miR-155 and miR-21 expression using real-time quantitative PCR in MSI (n = 10) and microsatellite stable (n = 10…”
Publikováno v Carcinogenesis (New York) (01. 04. 2013)
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20Hlavní autor Nazemalhosseini-Mojarad, Ehsan, Kishani Farahani, Roya, Mehrizi, Maryam, Baghaei, Kaveh, Yaghoob Taleghani, Mohammad, Golmohammadi, Mina, Peyravian, Noshad, Ashtari, Sara, Pourhoseingholi, Mohmad Amin, Asadzadeh Aghdaei, Hamid, Zali, Mohammad Reza“…) in Iranian colorectal cancer (CRC) patients. Methods BRAF and KRAS mutations and MSI status were assessed in 258 Iranian subjects with CRC…”
Publikováno v Journal of gastrointestinal cancer (01. 03. 2020)
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