Výsledky vyhledávání - "APC"
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3Hlavní autor Fujikura, Kohei, Akita, Masayuki, Ajiki, Tetsuo, Fukumoto, Takumi, Itoh, Tomoo, Zen, Yoh“…), histone methyltransferase (KMT2C, KMT2D), and DNA mismatch repair (MSH3, MSH6, PMS1). Combined with discovery and validation cohorts, mutations in APC or CTNNB1 were observed in 6/28 subjects (21…”
Publikováno v The American journal of surgical pathology (01. 12. 2018)
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4Hlavní autor Shur, Shira, Sommer, Anna K., Latchford, Andrew, Spier, Isabel, Katz, Lior H.“…In the majority of patients with a classical Familial Adenomatous Polyposis (FAP) a pathogenic APC germline variant is identified…”
Publikováno v Familial cancer (16. 04. 2025)
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5Hlavní autor Colaco, Jencia Carminha, Chandrasekaran, Arun Pandian, Karapurkar, Janardhan Keshav, Gowda, D.A. Ayush, Birappa, Girish, Rajkumar, Sripriya, Suresh, Bharathi, Ko, Nare, Hong, Seok-Ho, Oh, Seung Jun, Kim, Kye-Seong, Ramakrishna, Suresh“… The immunoprecipitation and Duolink proximity ligation assays (PLA) were used to determine the interaction between APC/CCdh1 and SLC35F2 proteins…”
Publikováno v Biochimica et biophysica acta. General subjects (01. 11. 2023)
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6Hlavní autor Herrero-Mendez, Angel, Almeida, Angeles, Fernández, Emilio, Maestre, Carolina, Moncada, Salvador, Bolaños, Juan P.“…The glycolytic enzyme Pfkfb3 is shown to be constitutively ubiquitylated by the APC/C ligase and degraded in neurons…”
Publikováno v Nature cell biology (01. 06. 2009)
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7Hlavní autor Marbun, Vania Myralda Giamour, Erlina, Linda, Lalisang, Toar Jean Maurice“…; hence it is essential to be discovered in a specific population. Until recently, there has been no known study describing APC, TP53, PIK3CA, KRAS, and MLH1 of CRC in Indonesian population…”
Publikováno v PloS one (16. 06. 2022)
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8Hlavní autor Abdel-Malak, Camelia, Darwish, Hossam, Elsaid, Afaf, El-Tarapely, Fatma, Elshazli, Rami“…) risk in several ethnic populations. The aim of this work is to assess the association of the APC I1307K and E1317Q polymorphisms with CRC risk among Egyptian subjects…”
Publikováno v Familial cancer (01. 01. 2016)
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9Publikováno v Biochimica et biophysica acta. General subjects (01. 11. 2023)“…: The immunoprecipitation and Duolink proximity ligation assays (PLA) were used to determine the interaction between APC/C and SLC35F2 proteins…”
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10Hlavní autor Wouters, Valérie M, Helderman, Roxan F C P A, Cameron, Kate, van der Hooff, Sander R, Torang, Arezo, van den Bergh, Saskia, Jackstadt, Rene, Sansom, Owen J, van Neerven, Sanne M, Medema, Jan Paul“…Colorectal cancer (CRC) can be divided into 4 subtypes of which consensus molecular subtype 4 (CMS4) is associated with metastasis and poor survival…”
Publikováno v Oncogene (06. 04. 2025)
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12Hlavní autor Liu, Jia, Yao, Qinyu, Xiao, Lei, Li, Fan, Ma, Wen, Zhang, Zihui, Xie, Xinya, Yang, Chunmiao, Cui, Qi, Tian, Ying, Zhang, Chao, Lai, Baochang, Wang, Nanping“… Here, we identified PECAM‐1 as a novel substrate of the APC/Cdh1 E3 ubiquitin ligase…”
Publikováno v Journal of cellular physiology (01. 03. 2020)
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14Hlavní autor Yanus, G.A., Akhapkina, T.A., Ivantsov, A.O., Preobrazhenskaya, E.V., Aleksakhina, S.N., Bizin, I.V., Sokolenko, A.P., Mitiushkina, N.V., Kuligina, E.Sh, Suspitsin, E.N., Venina, A.R., Holmatov, M.M., Zaitseva, O.A., Yatsuk, O.S., Pashkov, D.V., Belyaev, A.M., Togo, A.V., Imyanitov, E.N., Iyevleva, A.G.“… APC gene defects were identified in 26/38 (68%) subjects with colon polyposis; 8/26 (31%) APC mutations were associated with 2 known mutational hotspot…”
Publikováno v Clinical genetics (01. 05. 2018)
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15Hlavní autor Bozsik, Anikó, Butz, Henriett, Grolmusz, Vince Kornél, Polgár, Csaba, Patócs, Attila, Papp, János“…Familial adenomatous polyposis (FAP) is a hereditary cancer syndrome that occurs as a result of germline mutations in the APC gene…”
Publikováno v European journal of human genetics : EJHG (01. 07. 2023)
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16Hlavní autor Cuche, Céline, Mastrogiovanni, Marta, Juzans, Marie, Laude, Hélène, Ungeheuer, Marie-Noëlle, Krentzel, Daniel, Gariboldi, Maria Isabella, Scott-Algara, Daniel, Madec, Marianne, Goyard, Sophie, Floch, Camille, Chauveau-Le Friec, Gaëlle, Lafaye, Pierre, Renaudat, Charlotte, Le Bidan, Muriel, Micallef, Christine, Schmutz, Sandrine, Mella, Sébastien, Novault, Sophie, Hasan, Milena, Duffy, Darragh, Di Bartolo, Vincenzo, Alcover, Andrés“… Our recent work indicates that the APC protein is involved in various phases of both CD4 and CD8 T cells responses…”
Publikováno v Frontiers in immunology (18. 07. 2023)
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17APC mutations are common in adenomas but infrequent in adenocarcinomas of the non-ampullary duodenumHlavní autor Ishizu, Kenichi, Hashimoto, Taiki, Naka, Tomoaki, Yatabe, Yasushi, Kojima, Motohiro, Kuwata, Takeshi, Nonaka, Satoru, Oda, Ichiro, Esaki, Minoru, Kudo, Masashi, Gotohda, Naoto, Yoshida, Teruhiko, Yoshikawa, Takaki, Sekine, Shigeki“…), gastric-type adenoma, not otherwise specified ( n = 9), and foveolar-type adenoma ( n = 1). Protein-truncating APC mutations were highly frequent in adenomas…”
Publikováno v Journal of gastroenterology (01. 11. 2021)
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19Hlavní autor Wang, Jaw‐Yuan, Hsieh, Jan‐Sing, Chang, Mei‐Yin, Huang, Tsung‐Jen, Chen, Fang‐Ming, Cheng, Tian‐Lu, Alexandersen, Ketil, Huang, Yu‐Sheng, Tzou, Wen‐Shyong, Lin, Shiu‐Ru“…) after tumor resection. Recent advances in the detection of tumor DNA in the serum/plasma has opened up numerous new areas for investigation and new possibilities for molecular diagnosis. APC and K…”
Publikováno v World journal of surgery (01. 07. 2004)
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