Search Results - "CONTROLLED RELEASE"

Ultrasonic shock-wave as a control mechanism for liposome drug delivery system for possible use in scaffold implanted to animals with iatrogenic articular cartilage defects = Řízen...

Krátkodobá ultrazvuková sonikace o intenzitě I = 2 W·cm-2 a frekvenci f = 1 MHz je postačující pro rozbíjení liposomů. Vhodnější metodou pro otevírání liposomů je však použití …

Hnojiva s řízeným uvolňováním živin

Effect of slow release fertilizers on container-grown woody plants = Vliv hnojiv s pozvolným uvolňováním na růst dřevin v kontejnerech

Hnojiva s pozvolným uvolňováním (SRF) Silvamix Forte a Silvagen se testovala v dvouletých pokusech s dřevinami v kontejnerech (Pyracantha coccinea, Thuja occidentalis). Porovnávalo se několik …

Přírodou inspirované polymery citlivé na vnější podněty pro dopravu léčiv = Nature-Inspired Stimuli-Responsive Polymers for Drug Delivery

The review introduces potential advantages and limitations of applications of stimuli-responsive polymers for delivery of drugs, radionuclides and genes. Special emphasis is put on pH- and …

Modulace uvolňování léčiv z moderních perorálních a orálních hydrofilních matricových systémů na bázi hypromelosy = Modulation of Drug Release from Modern Oral Hypromellose Matrix...

Hypromellose, a semi-synthetic derivative of cellulose, is by far the most commonly used hydrophilic polymer for the development of oral controlled release dosage forms. Modulation of drug release can …

Lékové formy s elektronickým prvkem = Delivery Systems with an Electronic Element

Lékové formy s elektronickým prvkem je možné zařadit mezi jedny z nejmodernějších a nejinovativnějších lékových systémů posledních několika dekád. Inkorporace …

Amalgerol ovlivnil pšenici a řepku

Vodné disperze polymerů v obalech řídících uvolňování léčiv = Aqueous Polymer Dispersions in Film Coatings Controlling Drug Release

Aqueous polymer dispersions are used in preparation of film coatings controlling drug release. Various excipients such as plasticizers, surfactants, antiadhesives and pigments are often added to …

Modely in vitro - in vivo ve vývoji léčiv = In Vitro - In Vivo Models in Drug Development

Many experiments were performed to obtain in vitro - in vivo correlations for different drugs and formulations. Most of the correlations involve orally administered medical forms and those with …

Využití 3D tisku při přípravě a výrobě léků = 3D Print Technology in Manufacturing of Dosage Forms

3D printing is a rapidly growing technology. Besides its general industrial application, it is also applicable in manufacturing of dosage forms. Due to its inherent flexibility, it is predetermined to …

Pevné disperze málo rozpustných léčiv = Solid Dispersions of Poorly Water Soluble Drug

There has been a great interest in solid dispersions since 60's because it is one of the most promising methods to increase the low bioavailability of poorly water soluble drugs. Numerous studies …

Formulácia opiátových liekových foriem odolných voči zneužívaniu = Formulation of Abuse-Resistant Opiates Drug Dosage Forms

Prescription opioid abuse is a worldwide growing significant health problem. For that reason, the manufacturing of abuse-deterrent dosage forms is highly important. Alcohol is likely to interact with …

Lieky s mechanizmom pulzného uvoľňovania = Pulsatile Drug Delivery Systems

This review is focused on the basic principles of the delivery systems with a pulsatile release pattern. Such systems are designed according to the circadian rhythm of the body. Time-controlled, …

Termoplastifikovaný škrob a jeho aplikace = Thermoplastic Starch and its Applications

Starch is the most widely used bio-based biodegradable polymer. This contribution briefly reviews basic information about natural starch and focuses on preparation, properties and applications of …

Applications of mesoporous silica materials in food - a review

Mesoporous silica materials have been developed for some applications in the health field. These solids are used for the controlled release of bioactive molecules, as catalysts in the synthesis of …

Využití (meth)akrylátových kopolymerů v technologii matricových tablet s řízeným uvolňováním léčiva = The Use of (Meth)acrylic Copolymers in the Production of Matrix Tablets with C...

Eudragit ® polymers are widely used acrylic pharmaceutical excipients. Over recent years, they have often been applied in matrix tablets with controlled drug release to improve the therapeutic …

Účinky rodenticidních nástrah se sníženým obsahem antikoagulantů

Typy a příprava lipozomálních přípravků pro plicní podání = Types and Preparation of Liposomal Formulations for Pulmonary Administration

The use of liposomes as carriers for different types of drugs in formulations to be administered to the lungs brings a number of advantages, including the possibility of controlled release, …

Impact of fertilization strategies on the growth of lavender and nitrates leaching to environment

Horticultural industry significantly affects the environment. In particular, large amounts of irrigation water and fertilizers required for intensive plant production can result in an increased …

Aplikační možnosti disoluční metody s průtokovou celou = The Flow-Through Dissolution Method and Its Application Potentials

Flow-through cell dissolution method was implemented in pharmacopoeias in 1990 and since that time its usage significantly increased. It is employed in oral dosage forms with controlled drug release …